I think that if you're in Tel Aviv for only a day or two, you might benefit from first deciding what you're interested in seeing, and then looking for a nearby accommodation. The city is best experienced on foot, and you are going there at a reasonable time with respect to weather. So if you are able physically, you could reach your selected attractions by just walking to them. Public transportation is far from optimal (and non-existent on Saturdays), and I don't know if you like to be dependent on taxis. And if you are willing to stay not only in a hotel but in a short-term rental, there is no lack of accommodations spread out in the city.
Being a relatively young city, there are no major landmarks, but rather a nice variety of attractions that can be sampled in a short time. Any good website will list them.
A new "White City Center", an institute dedicated to Bauhaus architecture (for which Tel Aviv is known and has been recognized by UNESCO), will be inaugurated in a month (on Idelson Street).
The city has a great vibe to it and is very beautiful in parts. The beach promenade, markets, museums, gastronomy, architecture and historical sites all have their appeal, and Pauline has described some of these in her reports. People are friendly and usually speak English fairly well. Although, as I have said to Pauline, just remember that this is still the Middle East, so be prepared to see shabbiness and filth as well. And watch out for the electric scooters on the sidewalks - the transportation infrastructure is severely lacking.